Minster, David K. published the artcileThiazoles from cysteinyl peptides, Application of 2-(Methylthio)thiazole, the publication is Journal of Organic Chemistry (1978), 43(8), 1624-6, database is CAplus.
Glutathione derivative I underwent dehydrative cyclization to thiazoline II which was oxidized by NiO2 to thiazole III (R = Et, R1 = Ac) which was hydrolyzed to III (R = R1 = H), an amino acid derivative from the mushroom Xerocomus subtomentosus. Three thiazoline derivatives were oxidized by NiO2 to their corresponding thiazoles, whereas 5 other heterocyclic compounds were also dehydrogenated with NiO2. The thiazoline ring of phleomycin A2 was oxidized by NiO2 to the thiazole ring of bleomycin A2.
Journal of Organic Chemistry published new progress about 5053-24-7. 5053-24-7 belongs to thiazole, auxiliary class Thiazole,sulfides, name is 2-(Methylthio)thiazole, and the molecular formula is C4H5NS2, Application of 2-(Methylthio)thiazole.
Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica