Park, Hokoon’s team published research in Journal of Antibiotics in 47 | CAS: 5053-24-7

Journal of Antibiotics published new progress about 5053-24-7. 5053-24-7 belongs to thiazole, auxiliary class Thiazole,sulfides, name is 2-(Methylthio)thiazole, and the molecular formula is C4H5NS2, Name: 2-(Methylthio)thiazole.

Park, Hokoon published the artcileSynthesis and biological activities of C-3 heterocyclyl carbon-substituted new cephalosporins, Name: 2-(Methylthio)thiazole, the publication is Journal of Antibiotics (1994), 47(5), 606-8, database is CAplus and MEDLINE.

Title compounds I [R = (un)substituted 2-thienyl, 5-thiazolyl, 2-pyrrolyl, 2-furyl, 5-isoxazolyl] were prepared via reaction of 3-chloromethyl-7-phenylacetamidocephem with RSnBu3 and transacylation. Most I were superior to cefixime against gram-pos. organisms, but were inactive against Klebsiella aerogenes, Pseudomonas aeruginosa, and Enterobacter cloacae.

Journal of Antibiotics published new progress about 5053-24-7. 5053-24-7 belongs to thiazole, auxiliary class Thiazole,sulfides, name is 2-(Methylthio)thiazole, and the molecular formula is C4H5NS2, Name: 2-(Methylthio)thiazole.

Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica