Reddy, Ghanta Mahesh published the artcileIdentification and characterization of potential impurities of tizanidine hydrochloride, Application of 5-Chlorobenzo[c][1,2,5]thiadiazol-4-amine, the publication is Analytical Chemistry: An Indian Journal (2008), 7(8), 586-590, database is CAplus.
During the anal. of laboratory batches of Tizanidine HCl, six impurities were detected by a simple isocratic reverse-phase high performance liquid chromatog. (HPLC) whose area percentage ranged from 0.10 to 0.30%. A through study has been undertaken to isolate and characterize these impurities, LCMS was performed to identify the mass number of the impurities. The structures of the impurities characterized as: N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazole-4-amine hydrochloride [imp A], N-(5-chloro-2,1,3-benzothiadiazol-4-yl)thiourea (imp B), dimer of Tizanidine HCl (imp C), S-methyl-N-(5-chloro-2,1,3-benzothiadiazol-4-yl)-isothiouronium iodide (imp D), 4-amino-5-chloro-2,1,3-benzothiadiazole (imp E), and N,N-bis(5-chloro-2,1,3-benzothiadiazol-4-yl)-N-(4,5-dihydro-1H-imidazol-2-yl)guanidine (imp F).
Analytical Chemistry: An Indian Journal published new progress about 30536-19-7. 30536-19-7 belongs to thiazole, auxiliary class Other Aromatic Heterocyclic,Chloride,Amine, name is 5-Chlorobenzo[c][1,2,5]thiadiazol-4-amine, and the molecular formula is C6H4ClN3S, Application of 5-Chlorobenzo[c][1,2,5]thiadiazol-4-amine.
Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica