Berry, Craig R.’s team published research in Organic Letters in 9 | CAS: 5053-24-7

Organic Letters published new progress about 5053-24-7. 5053-24-7 belongs to thiazole, auxiliary class Thiazole,sulfides, name is 2-(Methylthio)thiazole, and the molecular formula is C4H5NS2, Formula: C4H5NS2.

Berry, Craig R. published the artcileCycloaddition Reactions of Thiazolium Azomethine Ylides: Application to Pyrrolo[2,1-b]thiazoles, Formula: C4H5NS2, the publication is Organic Letters (2007), 9(21), 4099-4102, database is CAplus and MEDLINE.

Thiazolium azomethine ylides, generated from 1,3-thiazoles equipped with a C-2 methanethiol group, participated in an efficient [3+2] cycloaddition reaction with acetylene derivatives to yield unique pyrrolo[2,1-b]thiazoles. The elimination of the methanethiol leaving group from the cycloadduct replaced the need for a sep. oxidation step and suppressed ring-opening side reactions. Products were obtained in short synthetic sequences to demonstrate their use as a scaffold for compound libraries.

Organic Letters published new progress about 5053-24-7. 5053-24-7 belongs to thiazole, auxiliary class Thiazole,sulfides, name is 2-(Methylthio)thiazole, and the molecular formula is C4H5NS2, Formula: C4H5NS2.

Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica