Mahapatra, G. N.’s team published research in Journal of the Indian Chemical Society in 33 | CAS: 56503-96-9

Journal of the Indian Chemical Society published new progress about 56503-96-9. 56503-96-9 belongs to thiazole, auxiliary class Thiazole,Amine,Naphthalene, name is 4-(Naphthalen-1-yl)thiazol-2-amine, and the molecular formula is C13H10N2S, Product Details of C13H10N2S.

Mahapatra, G. N. published the artcileBromination of 2-aminothiazoles and their use as possible fungicides and bactericides, Product Details of C13H10N2S, the publication is Journal of the Indian Chemical Society (1956), 527-31, database is CAplus.

Seventeen 4-aryl-2-aminothiazoles (I) were prepared and brominated to 5-bromo-4-aryl-2-aminothiazoles (II). The aryl group and the m.ps., resp., are : Ph, 153-4°, 103°; p-MeC6H4, 123-4°, 106°; p-EtC6H4, 107-8°, 112°; 3,4-Me2C6H3, 135-6°, 107°; 2,5-Me2C6H3, 177-8°, 187°; p-MeOC6H4, 204-5°, 152°; p-EtOC6H4, 230-1°, 98°; ο-HOC6H4, 139-40°, 221°; p-HOC6H4, 198-9°, 235°; p-BrC6H4, 176-7°, 192°; m-H2NC6H4, 170-1°, 207°; p-H2NC6H4, 174-5°, 200°; α-C10H7, 130-1°, 111°; β-C10H7, 150-1°, 168°; 2-thienyl, 107-8°, 217°; PhCH2CH2, 90-1°, 201°; and MeOC6H4CH2CH2, 97-8°, 197° (decomposition). The bactericidal activity was determined in terms of the maximum effective dilution (M. E.D.) at 10 min. exposure. The M.E.D. for Escherichia coli was 1:1000 (maximum) for I and 1:1000 to 1:4000 for II; for Staphylococcus aureus was 1:8000 (maximum) for I and 1:10,000 to 1:20,000 for II. The fungicidal activity against Alternaria brassicae was: II at 50 p.p.m. and I at 80 p.p.m. inhibited spore germination; II at 40 p.p.m. reduced spore germination to 15-20%.

Journal of the Indian Chemical Society published new progress about 56503-96-9. 56503-96-9 belongs to thiazole, auxiliary class Thiazole,Amine,Naphthalene, name is 4-(Naphthalen-1-yl)thiazol-2-amine, and the molecular formula is C13H10N2S, Product Details of C13H10N2S.

Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica