Park, Cheol-Min’s team published research in Bioorganic & Medicinal Chemistry Letters in 15 | CAS: 56503-96-9

Bioorganic & Medicinal Chemistry Letters published new progress about 56503-96-9. 56503-96-9 belongs to thiazole, auxiliary class Thiazole,Amine,Naphthalene, name is 4-(Naphthalen-1-yl)thiazol-2-amine, and the molecular formula is C13H10N2S, Computed Properties of 56503-96-9.

Park, Cheol-Min published the artcileNon-peptidic small molecule inhibitors of XIAP, Computed Properties of 56503-96-9, the publication is Bioorganic & Medicinal Chemistry Letters (2005), 15(3), 771-775, database is CAplus and MEDLINE.

Non-peptidic small mol. SMAC mimetics were designed and synthesized that bind to the BIR3 domain of XIAP using structure-based design. Substituted five-membered heterocycles such as thiazoles and imidazoles were identified that serve as replacements for peptide fragments of the lead. An example compound thus prepared and evaluated was an N-(thiazolyl)-L-alaninamide derivative (I).

Bioorganic & Medicinal Chemistry Letters published new progress about 56503-96-9. 56503-96-9 belongs to thiazole, auxiliary class Thiazole,Amine,Naphthalene, name is 4-(Naphthalen-1-yl)thiazol-2-amine, and the molecular formula is C13H10N2S, Computed Properties of 56503-96-9.

Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica