Quinazolone derivatives was written by Dash, B.;Mahapatra, Prasanta K.;Mahapatra, Prasanna K.. And the article was included in Journal of the Institution of Chemists (India) in 1983.HPLC of Formula: 6318-74-7 This article mentions the following:
Thiazolylquinazolones I [R = Me, Ph; R1 = thienyl, (un)substituted Ph; R2 = H, Ph, 2-Cl6H4, 4-ClC6H4] were prepared by aminolysis of benzoxazinones II with thiazolylamines III. Arylidenequinazolones I [R = R3C6H4CH:CH; R1 = (un)substituted Ph; R2 = H, Ph, 2-ClC6H4, 4-ClC6H4; R3 = 2-Cl, 4-Cl] were prepared by condensing I (R = Me) with R3C6H4CHO. At 500 ppm I inhibited Helminthosporium sativum by 50-70%, in vitro. In the experiment, the researchers used many compounds, for example, 4,5-Diphenylthiazol-2-amine (cas: 6318-74-7HPLC of Formula: 6318-74-7).
4,5-Diphenylthiazol-2-amine (cas: 6318-74-7) belongs to thiazole derivatives. Thiazoles are a class of five-membered rings containing nitrogen and sulfur with excellent antitumor, antiviral and antibiotic activities.Various laboratory methods exist for the organic synthesis of thiazoles. For example, 2,4-dimethylthiazole is synthesized from thioacetamide and chloroacetone.HPLC of Formula: 6318-74-7
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica