The scope and limitations of deuteration mediated by Crabtree’s catalyst was written by Ellames, George J.;Gibson, Jennifer S.;Herbert, John M.;McNeill, Alan H.. And the article was included in Tetrahedron in 2001.Recommanded Product: 5-Phenylthiazole This article mentions the following:
Exchange of protons for deuterons mediated by Crabtree’s catalyst is directed efficiently by a functional group containing an sp2-hybridized nitrogen or oxygen atom; more electron-rich substrates are, in general, deuterated more efficiently. The electronic effects of substituents in the arene ring are critical only where the directing group is poor, in which case exchange is generally promoted by electron donating substituents, but the exchange is impeded by bulky meta-substituents. In the experiment, the researchers used many compounds, for example, 5-Phenylthiazole (cas: 1826-13-7Recommanded Product: 5-Phenylthiazole).
5-Phenylthiazole (cas: 1826-13-7) belongs to thiazole derivatives. The thiazole ring is notable as a component of the vitamin thiamine (B1). Various laboratory methods exist for the organic synthesis of thiazoles. Prominent is the Hantzsch thiazole synthesis is a reaction between haloketones and thioamides.Recommanded Product: 5-Phenylthiazole
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica