Antitumor screening studies of oxazole derivatives was written by Popov, D.. And the article was included in Problemi na Onkologiyata in 1980.Recommanded Product: N-Phenylbenzo[d]thiazol-2-amine This article mentions the following:
Five i.p. injections of 120 mg I [74180-66-8] 120 mg II [79566-08-8], 3 mg III [1843-21-6], 100 mg IV; R = H (V) [79566-09-9] or 60 mg IV; R = Me (VI) [79566-10-2]/kg prolonged the life of mice inoculated with leukemia L-1210 by 1.04, 0, 12.22, 14.29, and 14.29%, resp. V, VI, and 6-MP prolonged the life of mice with adenocarcinoma 755 by 44.12, 52.71, and 98.24%, resp. V prolonged the life of mice with carcinosarcoma Walker 256 by 53%, and V and VI prolonged the life of mice with plasmocytoma MOPS-406 by 14.0 and 78.5%, resp. LD50 values of VI and III were 400 and 25 mg/kg, resp. The other compounds caused no mortality in mice at ≤400 mg/kg. In the experiment, the researchers used many compounds, for example, N-Phenylbenzo[d]thiazol-2-amine (cas: 1843-21-6Recommanded Product: N-Phenylbenzo[d]thiazol-2-amine).
N-Phenylbenzo[d]thiazol-2-amine (cas: 1843-21-6) belongs to thiazole derivatives. Thiazoles frequently appear in peptide studies. Thiazoles can also be used as protected formyl groups, which can be released in later stages of complex natural product synthesis. Various laboratory methods exist for the organic synthesis of thiazoles. Prominent is the Hantzsch thiazole synthesis is a reaction between haloketones and thioamides.Recommanded Product: N-Phenylbenzo[d]thiazol-2-amine
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica