A copper-mediated cross-coupling approach for the synthesis of 3-heteroaryl quinolone and related analogues was written by Shin, Sanghye;Kim, Yechan;Kim, Kiho;Hong, Sungwoo. And the article was included in Organic & Biomolecular Chemistry in 2014.Related Products of 1826-13-7 This article mentions the following:
An efficient and practical method for the direct cross-coupling between quinolones and a range of azoles was developed via copper-mediated C-H functionalization. This synthetic strategy provides a convenient access to a variety of C3-heteroaryl quinolones, quinolinone, nalidixic acid, uracil, pyridone, and chromone derivatives, which are prominent structural motifs in many biol. active compounds E.g., in presence of CuI and LiOCMe3 in 1,4-dioxane under N2 at 110 °C, coupling of 1-benzyl-3-iodo-4-quinolone with benzothiazole gave 80% 3-heteroaryl quinolone derivative (I). In the experiment, the researchers used many compounds, for example, 5-Phenylthiazole (cas: 1826-13-7Related Products of 1826-13-7).
5-Phenylthiazole (cas: 1826-13-7) belongs to thiazole derivatives. The thiazole ring is notable as a component of the vitamin thiamine (B1). Thiazole sulfonation occurs only under forcing conditions: the action of oleum at 250 °C for 3 hours in the presence of mercury(II) sulfate leads to 65% formation of 5-thiazole sulfonic acid.Related Products of 1826-13-7
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica