Chiral Pentacarboxycyclopentadiene-Based Bronsted Acid-Catalyzed Enantioselective Desymmetrization of Meso-Epoxides by 2-Mercaptobenzothiazoles was written by Yuan, Chao;Li, Jun;Li, Pingfan. And the article was included in ACS Omega in 2018.HPLC of Formula: 58759-63-0 This article mentions the following:
Enantioselective desymmetrization of meso-epoxides by 2-mercaptobenzothiazoles was realized by using the pentacarboxycyclopentadiene-based chiral Bronsted acid in combination of N-isopropylaniline as amine additive to give up to 90.5:9.5 er of the ring opening products. In the experiment, the researchers used many compounds, for example, 5-Nitrobenzothiazole-2-thiol (cas: 58759-63-0HPLC of Formula: 58759-63-0).
5-Nitrobenzothiazole-2-thiol (cas: 58759-63-0) belongs to thiazole derivatives. The higher aromaticity of thiazole is due to delocalization of a lone pair of sulfur electrons across the ring, which is evidenced by chemical shifts of ring hydrogen at δ 7.27 and 8.77 ppm (C2 and C4), indicating diamagnetic ring current.Various laboratory methods exist for the organic synthesis of thiazoles. For example, 2,4-dimethylthiazole is synthesized from thioacetamide and chloroacetone.HPLC of Formula: 58759-63-0
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica