Straightforward synthesis of 2-anilinobenzoxazoles and -benzothiazoles via mechanochemical ball-milling-promoted one-pot reactions was written by Zhang, Ze;Wang, Fang-Jian;Wu, Hao-Hao;Tan, Ya-Jun. And the article was included in Chemistry Letters in 2015.Related Products of 1843-21-6 This article mentions the following:
Under mechanochem. ball-milling and solvent-free conditions, a series of 2-anilinobenzoxazoles and 2-anilinobenzothiazoles were synthesized directly from the one-pot reaction of anilines, CS2, and 2-aminophenol and -thiophenol. This protocol exhibited the free or cheap use of a cyclodesulfurization reagent, no separation of in-situ generated isothiocyanate, short reaction time and simple work-up procedure. In the experiment, the researchers used many compounds, for example, N-Phenylbenzo[d]thiazol-2-amine (cas: 1843-21-6Related Products of 1843-21-6).
N-Phenylbenzo[d]thiazol-2-amine (cas: 1843-21-6) belongs to thiazole derivatives. The higher aromaticity of thiazole is due to delocalization of a lone pair of sulfur electrons across the ring, which is evidenced by chemical shifts of ring hydrogen at δ 7.27 and 8.77 ppm (C2 and C4), indicating diamagnetic ring current. Various laboratory methods exist for the organic synthesis of thiazoles. Prominent is the Hantzsch thiazole synthesis is a reaction between haloketones and thioamides.Related Products of 1843-21-6
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica