Thiazole Orange derivatives: Synthesis, fluorescence properties, and labeling cancer cells was written by Fei, Xuening;Gu, Yingchun;Ban, Ying;Liu, Zhijun;Zhang, Baolian. And the article was included in Bioorganic & Medicinal Chemistry in 2009.Recommanded Product: 5-Nitrobenzothiazole-2-thiol This article mentions the following:
A series of Thiazole Orange (TO) derivatives were synthesized and modified by introducing different substitutional groups on benzothiazole and 4-methylquinoline. All the TO derivatives were confirmed by 1H NMR and MS. TO derivative bearing NH2– was modified by folic acid and used to label breast cancer cells. The phenomenon of fluorescence enhancement was shown by the fluorescence spectra of TO derivatives and micrographs of the labeled breast cancer cells. It offered a new try in the aspect of labeling cells by the embedded dyes. In the experiment, the researchers used many compounds, for example, 5-Nitrobenzothiazole-2-thiol (cas: 58759-63-0Recommanded Product: 5-Nitrobenzothiazole-2-thiol).
5-Nitrobenzothiazole-2-thiol (cas: 58759-63-0) belongs to thiazole derivatives. Thiazoles in peptides or their ability to bind proteins, DNA and RNA has led to many synthetic studies and new applications. Electrophilic attack at nitrogen depends on the presence of electron density at nitrogen as well as the position and nature of substituent linked to the thiazole ring.Recommanded Product: 5-Nitrobenzothiazole-2-thiol
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica