Synthesis of 4-substituted imino-4H-benzo[d][1,3] thiazin-2-amines via palladium-catalysed isocyanide insertion in 2-bromophenylthioureas was written by Pandey, Garima;Bhowmik, Subhendu;Batra, Sanjay. And the article was included in RSC Advances in 2014.SDS of cas: 1843-21-6 This article mentions the following:
The palladium-catalyzed isocyanide insertion in 2-bromophenylthioureas resulted in the formation of 4-substituted imino-4H-benzo[d][1,3]thiazin-2-amines, e.g., I, via C-S cross coupling reaction of the intermediate imidoylpalladium species. The investigations into the substrate scope revealed that reactions of cyclohexyl isocyanide were successful with aromatic as well as aliphatic thioureas, whereas reactions of all other isocyanides (except Et 2-isocyanoacetate) were successful with aromatic thioureas only. In the experiment, the researchers used many compounds, for example, N-Phenylbenzo[d]thiazol-2-amine (cas: 1843-21-6SDS of cas: 1843-21-6).
N-Phenylbenzo[d]thiazol-2-amine (cas: 1843-21-6) belongs to thiazole derivatives. The thiazole ring is notable as a component of the vitamin thiamine (B1). Electrophilic attack at nitrogen depends on the presence of electron density at nitrogen as well as the position and nature of substituent linked to the thiazole ring.SDS of cas: 1843-21-6
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica