The formation of 1,3-benzothiazole derivatives from 2,2′-diaminodiphenyl disulfide. Sulfocyanation of 2,2′-diaminodiphenyl sulfide and its reaction with N-aryl isothiocyanates was written by Vinkler, E.;Klivenyi, F.. And the article was included in Acta Chimica Academiae Scientiarum Hungaricae in 1977.COA of Formula: C13H10N2S This article mentions the following:
Reaction of (2-H2NC6H4S)2 (I) with HSCN gave a mixture containing 80% II (R = H) and 20% III. Treatment of I with RNCS (R = Ph, p-ClC6H4, Me, p-BrC6H4) gave only II. O-H2NC6H4SH and o-HSC6HNC(:NH)H were intermediates in the reaction of I and HSCN to form II. In the experiment, the researchers used many compounds, for example, N-Phenylbenzo[d]thiazol-2-amine (cas: 1843-21-6COA of Formula: C13H10N2S).
N-Phenylbenzo[d]thiazol-2-amine (cas: 1843-21-6) belongs to thiazole derivatives. Thiazole rings are planar and aromatic. Thiazoles are characterized by larger pi-electron delocalization than the corresponding oxazoles and have therefore greater aromaticity. There are numerous natural products that possess a thiazole ring with broad pharmacological activities. Thiamine, also known as vitamin B1, possesses a thiazole ring linked with 2-methylpyrimidine-4-amine as hydrochloride salt.COA of Formula: C13H10N2S
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica