Nucleophilic addition of 2-phenylaminobenzothiazole to acrylic acid was written by Saprykina, V. A.;Ambartsumova, R. F.. And the article was included in Uzbekskii Khimicheskii Zhurnal in 1987.Category: thiazole This article mentions the following:
Addition of CH2:CHCO2H to 2-anilinobenzothiazole 5 h at 140° gave 57% benzothiazole I and 14% benzothiazoline II. Amination of 2-chlorobenzothiazole with PhNHCH2CH2CO2Me gave the Me ester of I which was saponified by H2SO4. In the experiment, the researchers used many compounds, for example, N-Phenylbenzo[d]thiazol-2-amine (cas: 1843-21-6Category: thiazole).
N-Phenylbenzo[d]thiazol-2-amine (cas: 1843-21-6) belongs to thiazole derivatives. Thiazoles are a class of five-membered rings containing nitrogen and sulfur with excellent antitumor, antiviral and antibiotic activities. Various laboratory methods exist for the organic synthesis of thiazoles. Prominent is the Hantzsch thiazole synthesis is a reaction between haloketones and thioamides.Category: thiazole
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica