An efficient synthesis of 2-aminobenzoxazoles and 2-aminobenzothiazoles from 2-aminophenols or 2-aminothiophenols and isoselenocyanates was written by Xie, Yuanyuan;Zhang, Fan;Chen, Xiaodong;Li, Jianjun. And the article was included in Heterocycles in 2010.Category: thiazole This article mentions the following:
An expeditious method to access 2-aminobenzoxazoles and 2-aminobenzothiazoles from various substituted 2-aminophenols and 2-aminothiophenol, resp., with isoselenocyanates in a one pot procedure is reported. Elemental Se precipitates nearly quant. in the reaction without any deselenizing agent and it can be reused. A possible mechanism for the formation of the target products is proposed. In the experiment, the researchers used many compounds, for example, N-Phenylbenzo[d]thiazol-2-amine (cas: 1843-21-6Category: thiazole).
N-Phenylbenzo[d]thiazol-2-amine (cas: 1843-21-6) belongs to thiazole derivatives. Thiazole rings are planar and aromatic. Thiazoles are characterized by larger pi-electron delocalization than the corresponding oxazoles and have therefore greater aromaticity. Thiazole is a versatile building block for the construction and lead generation of new drug discoveries. Numerous diazole-based compounds are in clinical use as anticancer, antileukemic, antiinflammatory, antiviral, antifungal, antirheumatic, immunomodulator, and antiparasitic agents.Category: thiazole
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica