Conformational analysis and electronic structure of phenylthiazoles and their protonated forms was written by Galasso, V.;Trinajstic, N.. And the article was included in Tetrahedron in 1972.Application of 1826-13-7 This article mentions the following:
The most probable conformation of 2-, 4-, and 5-phenylthiazole and their protonated forms was investigated using the extended Hueckel MO approach and it was found to be non-planar, the angle of twist about the interring linkage increasing in the order: 4- < 2- < 5-. For the energetically most favorable geometry the charge distribution calculated using the CNDO/2 (complete neglect of differential overlap) method is found to be consistent with the observed dipole moment. In the experiment, the researchers used many compounds, for example, 5-Phenylthiazole (cas: 1826-13-7Application of 1826-13-7).
5-Phenylthiazole (cas: 1826-13-7) belongs to thiazole derivatives. The thiazole ring has been identified as a central feature of numerous natural products, perhaps the most famous example of which is epothilone.Various laboratory methods exist for the organic synthesis of thiazoles. For example, 2,4-dimethylthiazole is synthesized from thioacetamide and chloroacetone.Application of 1826-13-7
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica