1,10-phenanthroline-catalyzed tandem reaction of 2-iodoanilines with isothiocyanates in water was written by Zhang, Wu;Yue, Yun;Yu, Dan;Song, Lei;Xu, Yang-Yang;Tian, Yu-Jie;Guo, Yu-Jun. And the article was included in Advanced Synthesis & Catalysis in 2012.Safety of N-Phenylbenzo[d]thiazol-2-amine This article mentions the following:
The 1,10-phenanthroline-catalyzed tandem reaction of 2-iodoanilines with isothiocyanates in water was carried out, which provides an environmentally benign, efficient and simple route for the preparation of 2-aminobenzothiazoles. The present tandem process shows broad substrate scope in the absence of transition metals and phase-transfer catalysts. © 2012 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. In the experiment, the researchers used many compounds, for example, N-Phenylbenzo[d]thiazol-2-amine (cas: 1843-21-6Safety of N-Phenylbenzo[d]thiazol-2-amine).
N-Phenylbenzo[d]thiazol-2-amine (cas: 1843-21-6) belongs to thiazole derivatives. Thiazoles frequently appear in peptide studies. Thiazoles can also be used as protected formyl groups, which can be released in later stages of complex natural product synthesis. The pyridine-type nitrogen in the thiazole ring deactivates the ring for electrophilic substitution reactions, which is further reduced in acid due to protonation of the thiazole ring.Safety of N-Phenylbenzo[d]thiazol-2-amine
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica