Reactions of new nitroethane derivatives; formation of new 1,5-benzothiazepines and benzothiazoles III was written by Bercin, Erdogan;Uysal-Gokce, Mehtap;Noyanalpan, Ningur. And the article was included in Journal of Faculty of Pharmacy of Gazi University in 1996.SDS of cas: 1843-21-6 This article mentions the following:
The reactions of [(aminophenyl)thio]phenylnitroethane derivatives, 2-NH2C6H4SCH(CH2NO2)C6H4R (2; R = H, Me) with isothiocyanates and benzaldehydes were studied. The reaction of 2 with isothiocyanates, R1NCS (R1 = Ph, 4-ClC6H4) gave 2-anilinobenzothiazoles I. Depending on the reaction temperature, 2 reacted with benzaldehydes (4-R1C6H4CHO, R1 = H, Cl, OMe, OEt) to give either 2-phenylbenzothiazole derivative II or 1,5-benzothiazepines III (R = H, Me, R1 = H). In the experiment, the researchers used many compounds, for example, N-Phenylbenzo[d]thiazol-2-amine (cas: 1843-21-6SDS of cas: 1843-21-6).
N-Phenylbenzo[d]thiazol-2-amine (cas: 1843-21-6) belongs to thiazole derivatives. Thiazole is a five-membered, unsaturated, planar, π-excessive heteroaromatic containing one sulfur atom and one pyridine-type nitrogen atom at position 3 of the cyclic ring system. The pyridine-type nitrogen in the thiazole ring deactivates the ring for electrophilic substitution reactions, which is further reduced in acid due to protonation of the thiazole ring.SDS of cas: 1843-21-6
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica