Jafari, Behzad et al. published their research in ChemistrySelect in 2019 | CAS: 615-20-3

2-Chlorobenzothiazole (cas: 615-20-3) belongs to thiazole derivatives. The thiazole ring has been identified as a central feature of numerous natural products, perhaps the most famous example of which is epothilone. Various laboratory methods exist for the organic synthesis of thiazoles. Prominent is the Hantzsch thiazole synthesis is a reaction between haloketones and thioamides.Recommanded Product: 2-Chlorobenzothiazole

Synthesis of 2-Alkynyl- and 2-Amino-12H-benzothiazolo[2,3-b]quinazolin-12-ones and Their Inhibitory Potential against Monoamine Oxidase A and B was written by Jafari, Behzad;Jalil, Saquib;Zaib, Sumera;Safarov, Sayfidin;Khalikova, Muattar;Khalikov, Djurabay;Ospanov, Meirambek;Yelibayeva, Nazym;Zhumagalieva, Shynar;Abilov, Zharylkasyn A.;Turmukhanova, Mirgul Z.;Kalugin, Sergey N.;Salman, Ghazwan Ali;Ehlers, Peter;Hameed, Abdul;Iqbal, Jamshed;Langer, Peter. And the article was included in ChemistrySelect in 2019.Recommanded Product: 2-Chlorobenzothiazole This article mentions the following:

The 2-alkynyl- and 2-aminobenzothiazolo[2,3-b]quinazolin-12-ones I (R = isopropylaminyl, diphenylaminyl, morpholin-4-yl, etc.) and II (Ar = Ph, 4-tert-butylphenyl, naphthalen-1-yl, etc.) have been synthesized by Palladium catalyzed Buchwald-Hartwig and Sonogashira reactions. Synthesized derivatives were further evaluated for their role as potential inhibitors of monoamine oxidase A and B (MAO-A and B) isoenzymes. Most compounds possess moderate to excellent inhibitory potential against MAO-A and MAO-B. The 2-amino-substituted derivatives show a significantly higher activity as compared to 2-alkynyl- and previously reported 2-aryl derivatives Studied compounds might be employed as novel monoamine oxidase inhibitors and may provide insights for the development of new drug candidates against neurol. diseases. In the experiment, the researchers used many compounds, for example, 2-Chlorobenzothiazole (cas: 615-20-3Recommanded Product: 2-Chlorobenzothiazole).

2-Chlorobenzothiazole (cas: 615-20-3) belongs to thiazole derivatives. The thiazole ring has been identified as a central feature of numerous natural products, perhaps the most famous example of which is epothilone. Various laboratory methods exist for the organic synthesis of thiazoles. Prominent is the Hantzsch thiazole synthesis is a reaction between haloketones and thioamides.Recommanded Product: 2-Chlorobenzothiazole

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica