Isolation and characterization of a highly virulent Edwardsiella piscicida strain responsible for mass mortality in marbled eel (Anguilla marmorata) cultured in Korea was written by Jung, Won Joon;Kwon, Jun;Giri, Sib Sankar;Kim, Sang Guen;Kim, Sang Wha;Kang, Jeong Woo;Lee, Sung Bin;Lee, Young Min;Oh, Woo Taek;Jun, Jin Woo;Park, Se Chang. And the article was included in Aquaculture in 2022.Product Details of 78110-38-0 This article mentions the following:
Edwardsiella infections have the potential to induce immense economic losses by affecting multiple fish species, and have been increasingly reported in aquaculture. Edwardsiella tarda, Edwardsiella hoshinae, and Edwardsiella ictaluri have all been previously associated with mass mortality. Recent technol. advances in bacterial identification have identified E. piscicida and E. anguillarum as important pathogens affecting global fisheries. Strains previously identified as E. tarda have been re-grouped based on new sequence data and phylogenetic studies. E. piscicida was classified as a novel species in 2012 and has since been reported to have caused mortality in diverse fish species in numerous countries that are potentially more threatening than the mortality caused by E. tarda. Eels are one of the most consumed fish species in Asia, and Anguilla japonica is a commonly reared species in fisheries. However, due to increasing global eel consumption, attempts to culture marbled eel (A. marmorata) have been recently carried out in many Asian countries including Korea. The external clin. signs of Edwardsiella piscicida- infected marbled eel (A. marmorata) were enlarged liver, hemorrhagic congestion at the base of fins and on the skin, as well as hemorrhagic ascites and multifocal abscesses were found in the liver. Histopathol. on E. piscicida- infected tissues revealed bacteremia, multifocal necrotizing hepatitis with vasculitis and splenitis with vasculitis. This study reports the first E. piscicida infection case responsible for mass mortality in A. marmorata cultured in Korea. Our study focused on the isolation and histopathol. characterization of this bacterial strain to better understand its damage on A. marmorata. In the experiment, the researchers used many compounds, for example, 2-((((Z)-1-(2-Aminothiazol-4-yl)-2-(((2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl)amino)-2-oxoethylidene)amino)oxy)-2-methylpropanoic acid (cas: 78110-38-0Product Details of 78110-38-0).
2-((((Z)-1-(2-Aminothiazol-4-yl)-2-(((2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl)amino)-2-oxoethylidene)amino)oxy)-2-methylpropanoic acid (cas: 78110-38-0) belongs to thiazole derivatives. Thiazole rings are planar and aromatic. Thiazoles are characterized by larger pi-electron delocalization than the corresponding oxazoles and have therefore greater aromaticity. The pyridine-type nitrogen in the thiazole ring deactivates the ring for electrophilic substitution reactions, which is further reduced in acid due to protonation of the thiazole ring.Product Details of 78110-38-0
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica