Synthesis and anti-inflammatory activity of 2-amino substituted benzothiazoles was written by Pattan, Shashikant R.;Pujar, V. D.;Dighe, Nachiket S.;Musmade, Deepak S.;Hiremath, S. N.;Shinde, H. V.;Laware, R. B.. And the article was included in Asian Journal of Research in Chemistry in 2010.HPLC of Formula: 89793-81-7 This article mentions the following:
New pyrazinyl-substituted 2-aminobenzothiazoles were prepared by multiple steps. The structures of the synthesized compounds were confirmed by m.p., TLC, IR, and H1 NMR. All the compounds showed promising anti-inflammatory activity. In the experiment, the researchers used many compounds, for example, 7-Nitrobenzo[d]thiazol-2-amine (cas: 89793-81-7HPLC of Formula: 89793-81-7).
7-Nitrobenzo[d]thiazol-2-amine (cas: 89793-81-7) belongs to thiazole derivatives. Thiazoles frequently appear in peptide studies. Thiazoles can also be used as protected formyl groups, which can be released in later stages of complex natural product synthesis. The pyridine-type nitrogen in the thiazole ring deactivates the ring for electrophilic substitution reactions, which is further reduced in acid due to protonation of the thiazole ring.HPLC of Formula: 89793-81-7
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica