Microwave-assisted synthesis of 2-amino-4-substituted phenyl-thiazole was written by Rahatgaonkar, Anjali;Rathod, A.. And the article was included in Asian Journal of Chemistry in 2006.SDS of cas: 57634-55-6 This article mentions the following:
The reaction time needed to synthesize substituted 2-amino-4-phenyl-thiazole was substantially reduced from hours to minutes by microwave irradiation Microwave assisted techniques have many advantages, i.e., very rapid reactions, low energy consumption and safe operation, high yield and less time. In the experiment, the researchers used many compounds, for example, 4-(2-Amino-4-thiazolyl)phenol (cas: 57634-55-6SDS of cas: 57634-55-6).
4-(2-Amino-4-thiazolyl)phenol (cas: 57634-55-6) belongs to thiazole derivatives. Thiazoles are a class of five-membered rings containing nitrogen and sulfur with excellent antitumor, antiviral and antibiotic activities. Thiazole sulfonation occurs only under forcing conditions: the action of oleum at 250 °C for 3 hours in the presence of mercury(II) sulfate leads to 65% formation of 5-thiazole sulfonic acid.SDS of cas: 57634-55-6
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica