A highly efficient palladium-catalyzed desulfitative arylation of azoles with sodium arylsulfinates was written by Wang, Min;Li, Dengke;Zhou, Wei;Wang, Lei. And the article was included in Tetrahedron in 2012.Related Products of 2942-06-5 This article mentions the following:
A highly efficient palladium-catalyzed direct desulfitative arylation of azoles at C2-position has been developed using sodium arylsulfinates as aryl sources. Azoles including benzoxazoles, benzothiazoles, oxazoles, thiazoles, and 1,3,4-oxadiazoles reacted with sodium arylsulfinates smoothly to generate the corresponding products in good to excellent yields, and various substitution patterns were tolerated toward the reaction. In the experiment, the researchers used many compounds, for example, 6-Nitrobenzothiazole (cas: 2942-06-5Related Products of 2942-06-5).
6-Nitrobenzothiazole (cas: 2942-06-5) belongs to thiazole derivatives. Thiazoles are a class of five-membered rings containing nitrogen and sulfur with excellent antitumor, antiviral and antibiotic activities. The pyridine-type nitrogen in the thiazole ring deactivates the ring for electrophilic substitution reactions, which is further reduced in acid due to protonation of the thiazole ring.Related Products of 2942-06-5
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica