Ring transformations of heterocyclic compounds. XVII. 2-(2,4,6-triarylphenyl) substituted dihydro-1H-imidazolium, dihydrothiazolium and thiazolium salts from 2-methyl derivatives by pyrylium and thiopyrylium ring transformations was written by Zimmermann, Thomas. And the article was included in Journal of Heterocyclic Chemistry in 1999.Category: thiazole This article mentions the following:
Some new 2-(2,4,6-triarylphenyl)-4,5-dihydro-1H-imidazolium perchlorates, -4,5-dihydrothiazolium perchlorates and -thiazolium perchlorates were obtained from their 2-Me analogs by a 2,6-[C5+C] ring transformation of 2,4,6-triarylpyrylium and -thiopyrylium salts in ethanol in the presence of an appropriate base. Spectroscopic data of the transformation products and structural influences on their formation via anhydrobases of the triarylpyrylium and -thiopyrylium salts are discussed. In the experiment, the researchers used many compounds, for example, 2-Methyl-4,5-dihydrothiazole (cas: 2346-00-1Category: thiazole).
2-Methyl-4,5-dihydrothiazole (cas: 2346-00-1) belongs to thiazole derivatives. Thiazoles frequently appear in peptide studies. Thiazoles can also be used as protected formyl groups, which can be released in later stages of complex natural product synthesis. The nitrogen in thiazole is sp2 hybridized and the lone pair of electrons localized on the nitrogen is less reactive due to increased aromatic character and decreased basicity. It is protonated and alkylated/acylated at nitrogen forming hydrochloride and quaternary thiazolium salt.Category: thiazole
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica