90533-23-6, 4-(3-Chlorophenyl)thiazol-2-amine is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: To a solution of 4-(3-bromopropoxy)benzaldehyde (200.00 mg, 0.82 mmol)and 4-phenylthiazol-2-amine (144.50 mg, 0.82 mmol) in DMF (15 mL),potassium carbonate (170.00 mg, 1.23 mmol) was added. The reaction mixturewas refluxed for 12 h. The reaction mixture was quenched with water,and extracted with toluene (20 mL*3). The combined organic layer waswashed with brine, dried with anhydrous sodium sulphate, concentratedunder vacuum, then purified by flash chromatography (petroleum ether:ethyl acetate = 3:1) to afford a colorless solid. Yield 32.3%. The procedure described for the synthesis of compound 3a can also beapplied to the synthesis of compounds 3b-o.
The synthetic route of 90533-23-6 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Liu, Jingbao; Deng, Xinxian; Jin, Yan; Xu, Buzhe; Liu, Wenlu; Jiang, Faqin; Fu, Lei; Pharmazie; vol. 70; 7; (2015); p. 446 – 451;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica