Rapid Access to a Broad Range of 6′-Substituted Firefly Luciferin Analogues Reveals Surprising Emitters and Inhibitors was written by Sharma, Deepak K.;Adams, Spencer T.;Liebmann, Kate L.;Miller, Stephen C.. And the article was included in Organic Letters in 2017.Recommanded Product: 80945-86-4 This article mentions the following:
Light-emitting firefly luciferin analogs contain electron-donating groups in the 6′-position, but the scope of known 6′-substitution remains narrow. A two-step route to a broad range of 6′-substituted luciferin analogs was developed to fill this void and enable more extensive study of the 6′-functionality. This chem. allowed direct access to “caged” amide and bright azetidine analogs, but also revealed thioether inhibitors and unexpectedly luminogenic aryl amine derivatives In the experiment, the researchers used many compounds, for example, 6-Bromo-2-chlorobenzothiazole (cas: 80945-86-4Recommanded Product: 80945-86-4).
6-Bromo-2-chlorobenzothiazole (cas: 80945-86-4) belongs to thiazole derivatives. Thiazoles in peptides or their ability to bind proteins, DNA and RNA has led to many synthetic studies and new applications. There are numerous natural products that possess a thiazole ring with broad pharmacological activities. Thiamine, also known as vitamin B1, possesses a thiazole ring linked with 2-methylpyrimidine-4-amine as hydrochloride salt.Recommanded Product: 80945-86-4
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica