Amphiphilic π-Allyliridium C,O-Benzoates Enable Regio- and Enantioselective Amination of Branched Allylic Acetates Bearing Linear Alkyl Groups was written by Meza, Arismel Tena;Wurm, Thomas;Smith, Lewis;Kim, Seung Wook;Zbieg, Jason R.;Stivala, Craig E.;Krische, Michael J.. And the article was included in Journal of the American Chemical Society in 2018.Safety of Thiazol-2-ylmethanamine This article mentions the following:
The first examples of amphiphilic reactivity in the context of enantioselective catalysis are described. Com. available π-allyliridium C,O-benzoates, which are stable to air, water and SiO2 chromatog., and are well-known to catalyze allyl acetate-mediated carbonyl allylation, are now shown to catalyze highly chemo-, regio- and enantioselective substitutions of branched allylic acetates bearing linear alkyl groups with primary amines. In the experiment, the researchers used many compounds, for example, Thiazol-2-ylmethanamine (cas: 55661-33-1Safety of Thiazol-2-ylmethanamine).
Thiazol-2-ylmethanamine (cas: 55661-33-1) belongs to thiazole derivatives. Thiazole is a five-membered, unsaturated, planar, π-excessive heteroaromatic containing one sulfur atom and one pyridine-type nitrogen atom at position 3 of the cyclic ring system. Electrophilic attack at nitrogen depends on the presence of electron density at nitrogen as well as the position and nature of substituent linked to the thiazole ring.Safety of Thiazol-2-ylmethanamine
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica