Acylation of 2-aminobenzothiazole and its 2- and 3-derivatives was written by Rozhkova, N. K.;Saprykina, V. A.. And the article was included in Uzbekskii Khimicheskii Zhurnal in 1975.Recommanded Product: 1843-21-6 This article mentions the following:
Pyrimidobenzothiazole I was obtained in 85% yield by acylation of II (R = R1 = H) with CH2:CHCOCl in dry Me2CO at room temperature II (R = Me, Ph, H, R1 = COCH:CH2, CO2Me, CO2Et) were obtained in 48-92% yields by acylation of II (R = Me, Ph, R1 = H) with R1COCl. Analogously obtained were 90-4% III (R = Me, Ph, R1 = COCH:CH2, CO2Me, CO2Et) by acylation of III (R1 = H) with R1COCl. In the experiment, the researchers used many compounds, for example, N-Phenylbenzo[d]thiazol-2-amine (cas: 1843-21-6Recommanded Product: 1843-21-6).
N-Phenylbenzo[d]thiazol-2-amine (cas: 1843-21-6) belongs to thiazole derivatives. Thiazole rings are planar and aromatic. Thiazoles are characterized by larger pi-electron delocalization than the corresponding oxazoles and have therefore greater aromaticity. There are numerous natural products that possess a thiazole ring with broad pharmacological activities. Thiamine, also known as vitamin B1, possesses a thiazole ring linked with 2-methylpyrimidine-4-amine as hydrochloride salt.Recommanded Product: 1843-21-6
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica