Reactions of 2-(arylamino)benzothiazoles with methyl acrylate was written by Ambartsumova, R. F.. And the article was included in Chemistry of Heterocyclic Compounds (New York)(Translation of Khimiya Geterotsiklicheskikh Soedinenii) in 2000.Application of 1843-21-6 This article mentions the following:
Addition of 2-(arylamino)benzothiazoles to the C:C bond of CH2:CHCO2Me gives a mixture of isomeric 2-(arylimino)-3-[2-(methoxycarbonyl)ethyl]benzothiazolines and 2-{aryl-[2-(methoxycarbonyl)ethyl]amino}benzothiazoles. Their thermal stability was studied. HPLC anal. was used to follow the dynamics of the accumulation of the compounds formed in the reaction mixtures In the experiment, the researchers used many compounds, for example, N-Phenylbenzo[d]thiazol-2-amine (cas: 1843-21-6Application of 1843-21-6).
N-Phenylbenzo[d]thiazol-2-amine (cas: 1843-21-6) belongs to thiazole derivatives. Thiazoles in peptides or their ability to bind proteins, DNA and RNA has led to many synthetic studies and new applications. Thiazole is a versatile building block for the construction and lead generation of new drug discoveries. Numerous diazole-based compounds are in clinical use as anticancer, antileukemic, antiinflammatory, antiviral, antifungal, antirheumatic, immunomodulator, and antiparasitic agents.Application of 1843-21-6
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica