Fungicidal activities and mass spectral studies of some Schiff bases derived from p-hydroxybenzaldehyde and their derivatives was written by Dash, B.;Mahapatra, P. K.;Panda, D.;Pattnaik, J. M. Mrs.. And the article was included in Journal of the Indian Chemical Society in 1984.Electric Literature of C15H12N2S This article mentions the following:
A new series of Schiff bases were prepared Condensation of 2-aminothiazoles and -benzothiazoles with p-HOC6H4CHO gave I [R = H, R1 = aryl, R2 = H, aryl, R2R2 = (un)substituted CH:CHCH:CH]. Chloroacetylation of I (R = H) followed by substitution with morpholine and piperidine gave I (R = morpholinoacetyl, piperidinoacetyl). Cycloaddition of I (R = H) with HSCH2CO2H yielded thiazolidinone derivatives II. I and II have satisfactory fungicidal activity against Curvularia at 500 ppm. The mass spectra of I (R = H) were discussed. In the experiment, the researchers used many compounds, for example, 4,5-Diphenylthiazol-2-amine (cas: 6318-74-7Electric Literature of C15H12N2S).
4,5-Diphenylthiazol-2-amine (cas: 6318-74-7) belongs to thiazole derivatives. The thiazole ring has been identified as a central feature of numerous natural products, perhaps the most famous example of which is epothilone. Thiazole is a versatile building block for the construction and lead generation of new drug discoveries. Numerous diazole-based compounds are in clinical use as anticancer, antileukemic, antiinflammatory, antiviral, antifungal, antirheumatic, immunomodulator, and antiparasitic agents.Electric Literature of C15H12N2S
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica