New Generation of Bioorthogonally Applicable Fluorogenic Dyes with Visible Excitations and Large Stokes Shifts was written by Herner, Andras;Estrada Girona, Gemma;Nikic, Ivana;Kallay, Mihaly;Lemke, Edward A.;Kele, Peter. And the article was included in Bioconjugate Chemistry in 2014.Category: thiazole This article mentions the following:
Synthesis of a set of new, azide bearing, bioorthogonally applicable fluorogenic dyes with large Stokes shifts is presented herein. To assess the fluorogenic performance of these new dyes the authors have labeled a genetically modulated, cyclooctyne-bearing protein in lysate medium. The labels produce specific signal with minimal background fluorescence. The authors also provide theor. insights into the design of such fluorogenic labels. In the experiment, the researchers used many compounds, for example, 2-Methyl-6-nitrobenzothiazole (cas: 2941-63-1Category: thiazole).
2-Methyl-6-nitrobenzothiazole (cas: 2941-63-1) belongs to thiazole derivatives. Thiazoles are a class of five-membered rings containing nitrogen and sulfur with excellent antitumor, antiviral and antibiotic activities. There are numerous natural products that possess a thiazole ring with broad pharmacological activities. Thiamine, also known as vitamin B1, possesses a thiazole ring linked with 2-methylpyrimidine-4-amine as hydrochloride salt.Category: thiazole
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica