Stability study on cefotiam hydrochloride and xylitol injection formulation was written by Hu, Zhong-jie;Zhou, Lei;Miao, Pei-hong. And the article was included in Xibei Yaoxue Zazhi in 2007.Application of 66309-69-1 This article mentions the following:
This paper aims to study the stability of cefotiam hydrochloride and xylitol injection formulation. Cefotiam hydrochloride and xylitol injection formulation was placed at room temperature (25°) for 8 h, and during this period its content change was determined by UV spectrophotometry. Its appearance, pH and particle changes were observed at the same time. It was found that cefotiam hydrochloride and xylitol injection formulation kept stable within 6 h. In the experiment, the researchers used many compounds, for example, (6R,7R)-7-(2-(2-Aminothiazol-4-yl)acetamido)-3-(((1-(2-(dimethylamino)ethyl)-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid dihydrochloride (cas: 66309-69-1Application of 66309-69-1).
(6R,7R)-7-(2-(2-Aminothiazol-4-yl)acetamido)-3-(((1-(2-(dimethylamino)ethyl)-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid dihydrochloride (cas: 66309-69-1) belongs to thiazole derivatives. Thiazoles are a class of five-membered rings containing nitrogen and sulfur with excellent antitumor, antiviral and antibiotic activities. Electrophilic attack at nitrogen depends on the presence of electron density at nitrogen as well as the position and nature of substituent linked to the thiazole ring.Application of 66309-69-1
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica