Copper Acetate-Catalyzed, Mild, Highly Efficient, and Practical Synthesis of Thiazoles and Aminothiazoles was written by Meshram, H. M.;Kumar, D. Aravind;Vara Prasad, B. Ramalinga. And the article was included in Synthetic Communications in 2009.Application of 74370-93-7 This article mentions the following:
A mild and highly efficient synthesis of thiazoles by the condensation of 伪-bromo ketones with thiourea in the presence of a catalytic amount of copper acetate at room temperature has been described. The method is applicable for a variety of aryl and alkyl 伪-bromo ketones. The catalyst is inexpensive, and substituted thiazoles are obtained in good yields. In the experiment, the researchers used many compounds, for example, 4-(tert-Butyl)thiazol-2-amine (cas: 74370-93-7Application of 74370-93-7).
4-(tert-Butyl)thiazol-2-amine (cas: 74370-93-7) belongs to thiazole derivatives. Thiazole rings are planar and aromatic. Thiazoles are characterized by larger pi-electron delocalization than the corresponding oxazoles and have therefore greater aromaticity.Various laboratory methods exist for the organic synthesis of thiazoles. For example, 2,4-dimethylthiazole is synthesized from thioacetamide and chloroacetone.Application of 74370-93-7
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica