Synthetic Route of 161797-99-5. Let¡¯s face it, organic chemistry can seem difficult to learn. Especially from a beginner¡¯s point of view. Like 161797-99-5, Name is Ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate. In a document type is Patent, introducing its new discovery.
The invention discloses a 2 – (3 – thiophene – 4 – hydroxy-phenyl) – 4 – methyl thiazole – 5 – carboxylic acid ethyl ester. The synthetic method is BuLi as catalyst, 2 – (4 – hydroxy-phenyl) – 4 – methyl thiazole – 5 – carboxylic acid ethyl ester and N, N – dimethyl formamide execute, then reacting with glacial acetic acid to produce 2 – (3 – thiophene – 4 – hydroxy-phenyl) – 4 – methyl thiazole – 5 – carboxylic acid ethyl ester. Synthesis in the reaction process does not adopt the hexamine, during the production of the sensitization factors may, at the same time production method is simple, environmental protection, the product has high purity, high yield, the cost is reduced, and at the same time improving the work efficiency, and is suitable for industrial production. (by machine translation)
The invention discloses a 2 – (3 – thiophene – 4 – hydroxy-phenyl) – 4 – methyl thiazole – 5 – carboxylic acid ethyl ester. The synthetic method is BuLi as catalyst, 2 – (4 – hydroxy-phenyl) – 4 – methyl thiazole – 5 – carboxylic acid ethyl ester and N, N – dimethyl formamide execute, then reacting with glacial acetic acid to produce 2 – (3 – thiophene – 4 – hydroxy-phenyl) – 4 – methyl thiazole – 5 – carboxylic acid ethyl ester. Synthesis in the reaction process does not adopt the hexamine, during the production of the sensitization factors may, at the same time production method is simple, environmental protection, the product has high purity, high yield, the cost is reduced, and at the same time improving the work efficiency, and is suitable for industrial production. (by machine translation)
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Reference£º
Thiazole | C3H7798NS – PubChem,
Thiazole | chemical compound | Britannica