With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.170232-69-6,(2,4-Dichlorothiazol-5-yl)methanol,as a common compound, the synthetic route is as follows.
To a solution of (2,4-dichloro-l,3-thiazol-5-yl)methanol (850 mg, 4.6 mmol) in anhydrous dichloromethane (40 mL) was added dropwise phosphorus tribromide (850 muL, 9.2 mmol). The mixture was stirred at room temperature for 3 hours. The solvent was evaporated. The residue was dried in vacuo, affording 5-(bromomethyl)-2,4- dichloro-l,3-thiazole. The product was used without further purification.
170232-69-6, As the paragraph descriping shows that 170232-69-6 is playing an increasingly important role.
Reference£º
Patent; CHLORION PHARMA, INC.; UNIVERSITE LAVAL; ATTARDO, Giorgio; TRIPATHY, Sasmita; WO2010/132999; (2010); A1;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica