With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.2289-75-0,4,5-Dimethylthiazol-2-amine,as a common compound, the synthetic route is as follows.
A mixture of 4,5-dimethylthiazol-2-ylamine (1.0 g, 7.8 mmol) and (2-bromo-ethoxy)benzene (1.9 g, 9.4 mmol) were heated neat to 85 0C for 19 hours. The mixture was cooled to ambient temperature and the residue was crystallized from isopropanol. The solid was collected by filtration and dried under vacuum to afford 1.3 g (50%) of the title compound. MS (DCIZNH3) mZz 249 (M+H)+, 2289-75-0
2289-75-0 4,5-Dimethylthiazol-2-amine 73238, athiazole compound, is more and more widely used in various.
Reference£º
Patent; ABBOTT LABORATORIES; WO2009/67613; (2009); A1;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica