556-90-1, 2-aminothiazol-4(5H)-one is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
556-90-1, To the magnetically stirred solution of 17 (232 mg, 2 mmol) in HOAc (7 mL), was added NaOAc (500 mg, 6 mmol). After 15 min 3,4-dimethoxybenzaldhyde (16a, 400 mg, 2.4 mmol) was added and the reaction mixture was heated under reflux for 72 h. The HOAc was removed under reduced pressure and the resultant solid was washed successively with water, methanol and EtOAc to obtain the desired products as solid. 10.2.1.1 5-(3,4-Dimethoxybenzylidene)-2-iminothiazolidin-4-one (14a) Yellow solid; mp > 200 C; 235 mg, 45% yield; IR (neat) numax = 3344, 2759, 1720, 1690, 1678 cm-1; 1H NMR (400 MHz, CD3SOCD3) delta = 9.35 (s, 1H), 9.09 (s, 1H), 7.54 (s, 1H), 7.08-7.16 (m, 3H), 3.80 (s, 6H); 13C NMR (100 MHz, CD3SOCD3): delta = 180.52, 175.39, 149.98, 148.81, 129.42, 126.62, 126.51, 122.77, 112.63, 111.98, 55.57, 55.38; HRMS (ESI-TOF): m/z calculated for C12H12N2O3S [M+Na]+, 287.0466; found 287.0461.
The synthetic route of 556-90-1 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Arfeen, Minhajul; Bhagat, Shweta; Patel, Rahul; Prasad, Shivcharan; Roy, Ipsita; Chakraborti, Asit K.; Bharatam, Prasad V.; European Journal of Medicinal Chemistry; vol. 121; (2016); p. 727 – 736;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica