Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, 121-66-4, Name is 5-Nitrothiazol-2-amine, SMILES is NC1=NC=C([N+]([O-])=O)S1, belongs to thiazoles compound. In a document, author is Zou, Rong, introduce the new discover, COA of Formula: C3H3N3O2S.
An enzyme-free DNA circuit-assisted MoS2 nanosheet enhanced fluorescence assay for label-free DNA detection
A fluorescence strategy for highly sensitive and selective detection of H5N1 DNA was proposed based on MoS2 nanosheets and catalytic hairpin assembly. This platform not only avoided any labeling but also reduced the background signal. In the absence of target, CHA could not be triggered and the thiazole orange and MBs complexes were adsorbed on the surface of MoS2 to quench the fluorescence of TO, resulting in low background signal. However, upon addition of target DNA, the CHA was initiated and produced plenty of MBs duplex which could be far away from the surface of MoS2 and bind to TO to enhance its fluorescence. This approach exhibited excellent sensitivity and specificity for H5N1 DNA with a detection limit of 7.5 pM, and realized the assay of H5N1 DNA in human serum samples. Furthermore, this platform could be expanded to detect other virus DNA by changing the corresponding molecular beacons, holding the potential of clinical application.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 121-66-4 is helpful to your research. COA of Formula: C3H3N3O2S.
Reference:
Thiazole | C3H3NS – PubChem,
,Thiazole | chemical compound | Britannica