81015-49-8, Name is 4-(2-Thiazolyl)phenol, molecular formula is C9H7NOS, belongs to thiazole compound, is a common compound. In a patnet, once mentioned the new application about 81015-49-8, HPLC of Formula: C9H7NOS
Novel triazole compounds with a dioxane ring were synthesized. Condensation of the diol precursor 10 with various aromatic aldehydes 11 – 13 under acidic conditions afforded a series of dioxane-triazole compounds 14 – 16. The antifungal activities of the compounds 14 – 16 were evaluated in vivo in mice infection models against Candida and Aspergillus species. High activities were seen for the derivatives with one or two double bond(s) and an aromatic ring substituted with an electron-withdrawing group in the side chain. Among the derivatives, R-102557 (16R: Ar=4-(2,2,3,3- tetrafluoropropoxy)phenyl) showed excellent in vivo activities against Candida, Aspergillus and Cryptococcus species. It also showed high tolerance in a preliminary toxicity study in rats.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.HPLC of Formula: C9H7NOS. In my other articles, you can also check out more blogs about 81015-49-8
Reference£º
Thiazole | C3H4635NS – PubChem,
Thiazole | chemical compound | Britannica