New learning discoveries about 39136-60-2

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39136-60-2, 5-Ethylthiazol-2-amine is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: These compounds were prepared by adapting a published procedure.2 To a mixture of 2, 4, 7a-n,7p and acid chloride (1.1 equiv.) in THF (20 mL) was added triethylamine (3 equiv.). The reaction mixture was stirred at room temperature for 15 min and quenched with distilled water. Following addition of a 0.1 N HCl aqueous solution, the product was extracted with DCM. The organic phase was washed with a saturated aqueous solution of NaHCO3, dried over MgSO4 and concentrated in vacuo. The residue was purified by silica gel column chromatography

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Reference£º
Article; Ishita, Keisuke; Stefanopoulos, Stavros; Khalil, Ahmed; Cheng, Xiaolin; Tjarks, Werner; Rappleye, Chad A.; Bioorganic and Medicinal Chemistry; vol. 26; 9; (2018); p. 2251 – 2261;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica