Synthetic Route of 3581-87-1. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 3581-87-1, Name is 2-Methylthiazole
A series of novel 5-methyl-2-phenylthiazole-4-substituted-heteroazole derivatives (6?15) have been synthesized. The structures of these compounds were established by IR, 1HNMR, Mass spectral data and elemental analyses. Compounds were evaluated for their anti-inflammatory and analgesic activities as well as gastric ulcerogenic effects. Derivatives 9, 10, 14 and 15 exhibited moderate to good anti-inflammatory and analgesic activities in carrageenan-induced rat paw edema and acetic acid-induced writhing in mice respectively, with low ulcerogenicity compared with the standard drug diclofenac sodium.
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Reference£º
Thiazole | C3H3751NS – PubChem,
Thiazole | chemical compound | Britannica