886361-30-4, Methyl 2-amino-5-(4-fluorophenyl)thiazole-4-carboxylate is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
In an inert atmosphere, copper(II)bromide (47.3 mmol, 1.0 eq) was suspended in MeCN (200 mL) and cooled to 5-10 C. followed by the addition of 3-methylbutylnitrite (71 mmol, 1.45 eq) over 15 min. To this reaction mixture the respective 2-aminothiazole derivative (47.3 mmol, 1 eq) was added in portions over 35 min at 5-10 C. The reaction mixture was then carefully heated to 65 C. and stirring continued for 2 h. The volatiles were removed under reduced pressure and the black residue was purified by FC (heptane/EtOAc, as the appropriate mixture) to give the products as slightly yellow oils or solids
886361-30-4, 886361-30-4 Methyl 2-amino-5-(4-fluorophenyl)thiazole-4-carboxylate 2782963, athiazole compound, is more and more widely used in various fields.
Reference£º
Patent; Aissaoui, Hamed; Boss, Christoph; Gude, Markus; Koberstein, Ralf; Sifferlen, Thierry; US2010/222328; (2010); A1;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica