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An efficient microwave assisted condensation of alpha-heteroarylamines with 3-dimethylamino-2-aryl-propenoates has been developed to synthesize various fused bi-heterocyclic compounds, including isothiazolo-, thiazolo-, imidazo-, and pyrimido-pyrimidinones as novel MCH1R antagonists.
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Reference£º
Thiazole | C3H6627NS – PubChem,
Thiazole | chemical compound | Britannica