4175-77-3, 2,4-Dibromothiazole is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
he mixture of compound 433a (5 g, 20.5 mmol), cyclopropyl boronic acid (2.12 g, 24.7 mmol), K3P04 (13.1 g, 61.7 mmol), Xantphos (0.6 g, 1.04 mmol) and Pd(OAc)2 (0.23 g, 1.04 mmol) in THF (140 mL) was stirred at 80 ¡ãC under N2 for about 15 hours. The reaction was complete detected by TLC (Petroleum Ether/EtOAc = 30: 1) and LCMS. The mixture was extracted with EtOAc (100 mL), water (50 mL). The combined organics was dried over Na2S04, purified with silica gel (Petroleum Ether /EtOAc = 50: 1) to provide compound 433b as oil (3.48 g, yield: 83.3percent)
4175-77-3, As the paragraph descriping shows that 4175-77-3 is playing an increasingly important role.
Reference£º
Patent; MERCK SHARP & DOHME CORP.; YU, Wensheng; TONG, Ling; KOZLOWSKI, Joseph A.; SELYUTIN, Oleg; CHEN, Lei; KIM, Jae-Hun; SHA, Deyou; RIZVI, Razia; SHANKAR, Bandarpalle; HU, Bin; ZHONG, Bin; WAI, Dahai; HAO, Jinglai; WEI, Wei; JI, Tao; ZAN, Shuai; WO2014/110705; (2014); A1;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica