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Sulfonylation of five-membered heterocycles via an SNAr reaction
An efficient, concise, and transition metal-free synthesis of functionalized sulfonylated five-membered heterocyclic compounds via an S NAr reaction has been developed. Using commercially available sodium sulfinates as sulfonylation reagents, various five-membered heterocyclic sulfones were obtained in good yields.
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Reference:
Thiazole | C3H2733NS – PubChem,
Thiazole | chemical compound | Britannica