In an article, published in an article, once mentioned the application of 120237-76-5, Name is 5-Methylthiazole-4-carboxylic acid,molecular formula is C5H5NO2S, is a conventional compound. this article was the specific content is as follows.Application In Synthesis of 5-Methylthiazole-4-carboxylic acid
5,6,7,8-TETRAHYDRO[1,2,4]TRIAZOLO[4,3-a]PYRAZ1NE DERIVATIVES AS P2X7 MODULATORS
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof wherein A is hydrogen, C1-4 alkyl, C3-6 cycloalkyl, C1-3 alkoxy, C1-3 alkoxy C1-4 alkyl, C1-2 fluoroalkyl, halogen, NR6 R7, optionally substituted heteroaryl (Het), or optionally substituted phenyl, and R1, R2, R3, R4, R5, R6 and R7 are as defined in the description. The compounds or salts are thought to modulate P2X7 receptor function and to be capable of antagonizing the effects of ATP at the P2X7 receptor. The invention also provides the use of the compound or salt in the treatment or prophylaxis of, for example, inflammatory pain, neuropathic pain, visceral pain, rheumatoid arthritis, osteoarthritis or neurodegenerative disorders.
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Reference：
Thiazole | C3H6529NS – PubChem,
Thiazole | chemical compound | Britannica