10200-59-6, Name is 2-Thiazolecarboxaldehyde, molecular formula is C4H3NOS, belongs to thiazole compound, is a common compound. In a patnet, once mentioned the new application about 10200-59-6, category: thiazole
Comparison of inhibitory activity of isomeric triazolopyridine derivatives towards adenosine receptor subtypes or do similar structures reveal similar bioactivities?
The synthesis of an array of 8-amino-2-aryl-[1,2,4]triazolo[1,5-a]pyridine- 6-carboxyl amide derivatives is described for the first time. A subset of 20 derivatives were compared to their isomeric 5-amino-2-aryl-[1,2,4]triazolo[1,5- a]pyridine-7-carboxyl amide counterparts with regard to their potential to inhibit the human adenosine 2a (hA2a) receptor and their selectivity against the human adenosine 1 (hA1) receptor. Based on the analysis of H-bond donor/acceptor capabilities of the isomeric triazolopyridine pairs it can be concluded that the H-bond donor strength of the free amino functionality is the main determinant for hA2a inhibitory activity and hA1 selectivity.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.category: thiazole. In my other articles, you can also check out more blogs about 10200-59-6
Reference：
Thiazole | C3H4122NS – PubChem,
Thiazole | chemical compound | Britannica