A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 5331-91-9, Name is 5-Chlorobenzo[d]thiazole-2(3H)-thione, molecular formula is C7H4ClNS2. In a Article，once mentioned of 5331-91-9, Application In Synthesis of 5-Chlorobenzo[d]thiazole-2(3H)-thione
Transition-metal-free formal sonogashira coupling and alpha-carbonyl arylation reactions
Transition-metal-free formal Sonogashira coupling and alpha-carbonyl arylation reactions have been developed. These transformations are based on the nucleophilic aromatic substitution (SNAr) of beta-carbonyl sulfones to electron-deficient aryl fluorides, producing a key intermediate that, depending on the reaction conditions, gives the aromatic alkynes or alpha-aryl carbonyl compounds. The development of these reactions is presented and, based on investigations under basic and acidic conditions, mechanisms have been proposed. To develop the formal disclosed that expands the reaction concept. The scope of these reactions is demonstrated for the synthesis of Sonogashira and alpha-carbonyl arylated products from a range of electron-deficient aryl fluorides with a variety of functional groups and aryl-, heteroaryl-, alkyl-, and alkoxy-substituted sulfone nucleophiles. These transition-metal-free reactions complement the metal-catalyzed versions in terms of substitution patterns, simplicity, and reaction conditions.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Application In Synthesis of 5-Chlorobenzo[d]thiazole-2(3H)-thione. In my other articles, you can also check out more blogs about 5331-91-9
Reference：
Thiazole | C3H6266NS – PubChem,
Thiazole | chemical compound | Britannica